Generic Name


Therapeutic Category



Metronidazole 400mg Tablets

Metronidazole 200mg/5ml Suspension



    MET 400

    Each film coated tablet contains:

    Metronidazole BP                                    400mg
     MET 200 is a yellow, circular biconvex film-coated tablet with 'T' scored on one side
     MET 200

    Each film coated tablet contains:

    Metronidazole BP                                   200mg
     MET 400 is ayellow oblong film coated tablet with break line on one side
     MET Suspension  Each 5 ml of the suspension contains:

    Metronidazole Benzoate IP equivalent to Metronidazole                                          200mg 

     MET suspension contains yellow colored suspension filled in 60 ml amber coloured PET bottle

    Pharmacotherapeutic Group: Antibiotic, antiprotozoal agent

    Pharmacodynamic properties: Metronidazole exerts antimicrobial effects in an anaerobic environment. The 5 nitro group undergoes reductive transformation to an active intermediate which then exerts an inhibitory effect against DNA. The reduced metabolite also causes a loss of the helical structure of DNA with subsequent DNA strand breakage.

    Pharmacokinetic properties:

    Absorption:Readily absorbed from the GI tract (oral), absorption delayed by the food. Time to peak plasma concentration:1-2 hr (oral). Bioavailability: 80%

    Distribution: Widely distributed in most body tissues and fluids. Crosses the placenta and enters breast milk. Plasma protein binding: <20%

    Metabolism: Undergoes hepatic metabolism by side chain oxidation and glucoronide formation.

    Excretion: Via urine (as metabolites) and faeces (small amounts). Elimiantion half-life: 8 hr


     Anaerobic bacterial infections, amoebiasis, giardiasis, trichomoniasis, vaginosis, amoebiac liver abscesses, H. pylori infections, ulcerative gingivitis, periodontal infections, pelvic inflammatory diseases.


    Adults: 1 tablet three times daily for 5 days.


    1-3 years: 5ml three times daily for 5 days;

    3-7 years: 100-200 mg 4 times daily;

    7-10 years: 200-400 mg three times daily;

    Doses are given for 5-10 days.




    • Tablets should be taken with food.

    Food Interaction: 

    • Fast heartbeats, redness under the skin, nausea and vomiting can be seen with alcohol.

    Pregnancy:   Category B

    Nursing Mothers: Metronidazole can pass into breast milk and may harm a nursing baby. Do not breast-feed while using metronidazole.

    Storage:  Store tablets at room temperature away from moisture and heat.

    Missed dose: 

    • Take the missed dose as soon as you remember
    • Skip the missed dose if it is almost time for your next scheduled dose
    • Do not take extra medicine to make up the missed dose.
    • Complete the course of the medication.


    Hypersensitivity, blood dyscrasias, active CNS disease, serious neurological disease, seizure, hepatic failure, first trimester pregnancy


    Renal and hepatic impairment, avoid alcohol


    Seizures, headache, dizziness, peripheral neuropathy, unpleasant metallic taste, furred tongue, GI disturbances, rashes, urticaria, pruritus, raised liver enzymes values, flatulence, nausea


    Acute psychosis with disulfiram. Synergistic effect with other antimicrobials


    MET 200: Each box contains 20 strips of 10 tabs packed in blisters.

    MET 400: Each box contains 20 strips of 10 tabs packed in blisters.

    MET Suspension: Each phial is supplied with50 ml suspension.