Generic Name


Therapeutic Category



Cephalexin 500mg Capsules

Cephalexin 100mg/1ml Drops

Cephalexin 125mg/5ml Dry Syrup

Cephalosporin Antibiotic


    LEXIN 500

    Each capsule contains:

    Cefalexin IP equivalent to Anhydrous Cefalexin      500mg

     LEXIN 500 is a size '0' plain hard gelatin capsule with blue cap and grey body filled with white to yellowish blend of granular powder
     LEXIN Dry Syrup

    Each 5 ml of the reconstituted suspension contains:

    Cefalexin IP equivalent to Anhydrous Cefalexin      125mg

     LEXIN DRY SYRUP contains white opaque HDPE bottle with circular mark for 60 ml on the outer side filled with slight white blend of granular powder 
    LEXIN DROPS  LEXIN DROPS: Each 1 ml of the reconstituted suspension contains:

    Cefalexin                                                        100mg

    LEXIN DROPS contains white blended granules and powder filled in 78 ml overflow capacity amber colored bottle with outer ring at 60 ml volume for reconstitution

    Pharmacotherapeutic Group: First generation cephalosporin antibiotics

    Pharmacodynamic properties: Cefalexin binds to one or more of the penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall, thus inhibiting biosynthesis and arresting cell wall assembly resulting in bacterial cell death.

    Pharmacokinetic properties:

    Absorption: Almost completely absorbed from the GI tract with peak plasma concentrations after 1 hr (oral); may be delayed if taken with food.

    Distribution: Widely distributed but does not penetrate the CSF; bile (therapeutic concentrations). Crosses the placenta and enters the breast milk (small amounts). Protein binding: Up to 15%

    Excretion: Via the urine within 6 hr by glomerular filtration and renal tubular secretion (>80% as unchanged); via the bile. May be removed by haemodialysis and peritoneal dialysis; elimination half-life: 1 hr


    Bone and joint infections, genitourinary tract infections, skin and soft tissue infections, otitis media, respiratory tract infections, uncomplicated cystitis 


    Adult: 500mg QID;

    Child: 25-100mg/kg daily in divided doses.




    • May be taken with or without food.

    Pregnancy:   Category B

    Nursing Mothers: Cefalexin can pass into breast milk and may harm a nursing baby. Do not breast-feed while using cefalexin.

    Storage:  Store capsules at room temperature (25°C) and in an air-tight container. 

    Missed dose: 

    • Take the missed dose as soon as you remember
    • Skip the missed dose if it is almost time for your next scheduled dose
    • Do not take extra medicine to make up the missed dose.
    • Complete the course of the medication.


    Hypersensitivity to cephalosporins


    Hypersensitivity to penicillins; pseudomembranous colitis; renal failure; pregnancy and lactation.


    Severe AEs: Anaphylactic reactions; nephrotoxicity General AEs: Hypersensitivity, GI disturbances, eosinophilia, neutropenia, leucopenia, thrombocytopenia. abdominal pain, angioedema, dyspepsia


    Serious drug interactionIncreased nephrotoxicity with aminoglycosides and furosemide.

    Probenecid produces higher and prolonged serum levels.


    LEXIN 500: Each box is supplied with 10 strips with 10 capsules in each.

    LEXIN DS: Each phial is supplied with 60 ml DS volume to be reconstituted.

    LEXIN Drops: Each phial is supplied with 10 ml volume to be reconstituted