Generic Name


Therapeutic Category


Salbutamol + Bromhexine

Salbutamol 2mg + Bromhexine 4mg/5ml Syrup




    Each 5 ml contains
    Salbutamol Sulphate BP equivalent to Salbutamol       2mg

    Bromhexine Hydrochloride BP                                  4mg

    Yellow colored, flavoured clear syrup, packed in 100 ml amber coloured PET bottle and sealed with ROPP cap.



    Administration:Should be taken on an empty stomach. Take 1hr before or 2 hr after meals.

    Pregnancy: Salbutamol- Category C

                       Bromhexine- Category A

    Storage: Store between 20-25 °C

    Missed dose: Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


    Pharmacotherapeutic Group: β2-adrenoreceptor agonist and Mucolytic Agents.

     Pharmacodynamic Properties:

    Salbutamol is a β2 adrenergic agonist and thus it stimulates β2 adrenergic receptors. Binding of salbutamol to the β2 receptors results in the relaxation of the bronchial smooth muscles. Salbutamol also inhibits the release of bronchoconstricting agents from the mast cells, inhibits the microvascular leakage and enhances the muciliary clearance.

    Bromhexine acts on the mucus at the formative stages in the glands within the mucus secreting cells. It destroys the structure of the acid mucopolysaccharide fibres in the mucoid sputum and produces less viscous mucus, which is easier to expectorate.


    Asthma, Bronchitis, Emphysema, Bronchospasm, Chronic Obstructive Pulmonary Disease (COPD), Exercise Induced Bronchospasm


    Adult: 2-4mg (up to 8mg) three times daily.Child: 2mg three times daily.


    Fine skeletal muscle tremor especially hands, tachycardia, palpitation, muscle cramps, headache, paradoxical bronchospasm, angioedema, urticaria, hypotension and collapse.

    Potentially Fatal: Potentially serious hypokalaemia after large doses.


    Pregnancy, mild to moderate pre-eclampsia, arrhythmias, hyperthyroidism, hypertension, diabetes mellitus, myocardial insufficiency, susceptibility to QT-interval prolongation. Monitor serum potassium levels. In women treated for premature labour, monitor hydration status, cardiac and respiratory function minimise volume of infusion fluid. Discontinue treatment if patient develops signs of pulmonary oedema.


    Diuretics, corticosteroids and xanthines may augment hypokalaemia. Cardiovascular effects potentiated by Monoamine-oxidase inhibitors, Tricyclic antidepressants, sympathomimetics. Reduces serum levels of digoxin. Hypokalaemia induced by salbutamol increases the risk of digitalis toxicity. Blood Pressure should be closely monitored if linezolid is used concurrently with salbutamol.


    Eclampsia and severe pre-eclampsia, intra-uterine infection, intra-uterine foetal death, antepartum haemorrhage, placenta praevia and cord compression, threatened miscarriage, cardiac disease.


    ASMAREX PLUS: Each bottle contains 100ml of syrup