Mupirocin 2% w/w Ointment
Mupirocin USP 2%w/w
|5 g of white semisolid ointment filled in a lami tube.|
Pregnancy: Category B
Nursing Mother: There is no information on the excretion of ROCIN in milk. If a cracked nipple is to be treated, it should be thoroughly washed prior to breast feeding.
Storage: Store at room temperature protected from light and heat; Do not refrigerate; Keep out of reach of children.
Missed dose: If you forget to apply the ointment, apply it as soon as you remember; If your next dose is due within an hour, skip the missed dose; Do not use a double dose to make up for a forgotten dose.
Pharmacotherapeutic Group: Antibiotic
Pharmacodynamic properties: ROCIN (Mupirocin) inhibits isoleucyl transfer-RNA synthetase, thereby arresting bacterial protein synthesis. It is active against gram-positive and some gram-negative bacteria. Mupirocin is rapidly metabolized when it reaches the systemic circulation hence it is used only topically.
Absorption: After topical application, mupirocin is only very minimally absorbed systemically through intact skin (<0.3%) and that which is absorbed is rapidly metabolised to the antimicrobially inactive metabolite, monic acid. Penetration of mupirocin into the deeper epidermal and dermal layers of the skin is enhanced in traumatised skin and under occlusive dressings
Secondary infected traumatic skin lesions; Minor burns; Prophylaxis, infection of hair root and boils; Open wounds; Impetigo.
Apply the ointment in the affected area three times daily for 10 days. The treated area may be covered by a dressing.
Mucosal surface of eye; Pregnancy and lactation; Renal Impairment; Children < 2 months.
ADVERSE DRUG REACTIONS
Burning, stinging, pain, itching, erythema, dryness, tenderness, dermatitis and rash.
Do not mix with other preparations as there is a risk of dilution, resulting in a reduction of the antibacterial activity and potential loss of stability of the mupirocin in the ointment unless directed by the doctor.
Each tube contain 5g of ointment.