Clotrimazole 1% w/w Cream
Clotrimazole IP 1% w/w
15 g of white semisolid cream filled in a collapsible aluminum tube.
Pregnancy: Category B
Storage: Store between 2-30°C.
Missed Dose: If you miss a dose use it as soon as you remember; If it is near the time of next dose skip the missed dose and resume your usual dosing schedule; Do not double the dose to make up the missed dose.
Pharmacotherapeutic Group: Antifungal agent
Pharmacodynamic properties: CLOTIME (Clotrimazole) acts against fungi by inhibiting 14α demethylase enzyme thus prevent the conversion of lanosterol to ergosterol. Inhibition of ergosterol synthesis leads to structural and functional impairment of the fungal cytoplasmic membrane.
Pharmacokinetic properties: Minimally absorbed from intact or inflamed skin into human blood circulation.
Superficial candidiasis; Oral thrush; Athlete's foot, Vaginal yeast infection; Jock itch
Apply 2-3 times daily in affected area for 2-4 weeks. Treatment should be continued for atleast1month for dermatophyte infection and at least 2 weeks for candida infection.
Pregnancy and lactation; Use of rubber contraceptive (reduce the effectiveness)
ADVERSE DRUG REACTIONS
Erythema, stinging, irritation; hypersensitivity reactions; contact dermatitis
Antagonism with polyene antibiotics.
CLOTIME: Each tube contains 15g of cream